Comprehensive bio-simulation from genes to a body is one of the most important research topics in 21st century. However, no single model or simulator can cover whole-body bio-system. Therefore, it is essential to develop environment for integrating heterogeneous bio-simulators. In this article, three types of key issues for integration of bio-simulators are discussed: (1) a wide variety of scales (time and spatial) should be handled, (2)various physical phenomena should be handled, (3) there are needs for distributed management of simulators. In addition, survey results of current status of bio-simulation environments are also reported.
By: Makoto Kano
Published in: RT0559 in 2007
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