Model Driven Approach for Biomedical Data Integration

A core challenge in biomedical data integration is to enable semantic interoperability between its various stakeholders as well as other interested parties. Promoting the adoption of worldwide accepted information standards along with common controlled terminologies is the right path to achieve that. This paper describes a solution to this fundamental problem by proposing an approach of semantic data integration based on information models serving as a common language to represent health data, coupled with a technology that is able to represent the data semantics. We used the HL7 v3 Reference Information Model (RIM) [1] to derive a specific data model for the integrated data, the Web Ontology Language (OWL) [2] to build an ontology that harmonizes the metadata from the disparate data sources, the Unified Modeling Language (UML) [3] to model the data representation, and the Object Constraint Language (OCL) [4] to specify UML model constraints. The Essential Hypertension Summary CDA document and related models are derived from Hypergenes, a European Commission funded project [5] exploring the Essential Hypertension disease model.

By: David Carlson; Ariel Farkash; John T. E. Timm

Published in: H-0284 in 2010


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